针刺研究

2017, v.42(01) 85-89

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针刺镇痛的新思路——针灸参与疼痛多维度调节的可行性
New Trains of Thoughts About Acupuncture Analgesia—Acupuncture Analgesia May Involve Multi-dimensional Regulation of Pain

方剑乔;邵晓梅;
FANG Jian-qiao;SHAO Xiao-mei;Zhejiang University of Traditional Chinese Medicine;

摘要(Abstract):

随着疼痛研究的推进,研究者逐渐认识到疼痛包括痛感觉、痛情绪、痛认知3个维度。3个维度之间相互影响又相对独立。疼痛研究已经从伤害性感受的单一模式向"疼痛-情绪-认知"的多维度模式转变。中医对疼痛病因提出了不通则痛、因病致郁等经典论述,体现了疼痛的多维度认识。针灸镇痛历史悠久,作用明确,而且初步研究发现针灸对痛诱发的情绪和认知改变都有积极的干预作用。因此对针刺镇痛的机制研究和临床应用的推广,如能从疼痛的多维度开展,必将创新针刺镇痛的研究理念,拓展针刺镇痛的研究领域,从而开创针刺镇痛更广阔的应用前景。
With the development of pain study,researchers gradually recognized that pain is composed of three main dimensions,namely"sensory-discriminative""affective-motivational"and"cognitive-evaluative"which influence each other and are also independent from each other.Pain study has shifted away from focusing on the single mode of nociception to the multi-dimensional mode of sensory-affection-cognition.It is held early in traditional Chinese medicine that"when there is a stoppage,there is apain"and a worsening disease may induce depression,which has already shown a multi-dimensional recognition about pain.Acupuncture therapy has been considered to be an effective adjuvant approach for relieving pain.In the present paper,the authors introduced applicability of acupuncture analgesia by modulating the abovementioned multi-dimensions of pain from the following 4aspects:1)multi-dimensions of pain and related brain regions;2)recognitions of traditional Chinese medicine about pain;3)development of researches on acupuncture analgesia,including a)balancing activities of endogenous analgesic and algogenic substances,and triggering intracellular mitogen-activated protein kinase(MAPK)signaling to reduce algesia,b)improving psychological symptoms of patients with depression,anxiety,insomnia,etc.,c)modulating functional activities of some common brain regions(as hippocampus,anterior cingutate,frontal lobe of cerebral cortex,etc.)sharing both pain information and learning-memory processing.Hence,the authors hold that if the clinical study and application and experimental researches conducted on the underlying mechanisms of acupuncture analgesia extend towards the multi-dimensions of pain,a series of new concepts or thoughts will be brought out,thereby possibly opening a bright applicable prospect for acupuncture analgesia.

关键词(KeyWords): 针刺镇痛;疼痛;多维度;感觉;情绪;认知
Acupuncture analgesia;Pain;Multi-dimensions;Sensation;Affection;Cognition

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金(No.81473772、81574056);;浙江省医药卫生科技项目省部共建项目(No.WKJ-ZJ-1419);;浙江省自然科学基金(No.LY15H270009)

作者(Authors): 方剑乔;邵晓梅;
FANG Jian-qiao;SHAO Xiao-mei;Zhejiang University of Traditional Chinese Medicine;

DOI: 10.13702/j.1000-0607.2017.01.016

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