针刺研究

1999, (04) 307-310

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针刺对肥胖大鼠作用的形态学观察
Morphological Observation on Acupuncture Effect on Obese Rat

刘志诚,孙凤岷,王耿,魏群利,苏静,许建阳,项晓人
Liu Zhicheng, et al (Nanjing University of TCM, Nanjing, 210029 )

摘要(Abstract):

本文采用高脂饲料喂养大鼠制造肥胖模型。应用光学和电子显微镜观察肥胖大鼠脂肪组织、小肠粘膜、肝组织形态,以及针刺后发生的形态学变化。结果显示,肥胖大鼠脂肪组织、小肠粘膜、肝组织均出现了形态学的异常。褐色脂肪细胞体积增大、充盈,脂滴增大,胞质内线粒体减少,细胞间隙变窄,毛细血管减少。针刺治疗后,上述形态学的异常均出现逆转,这种变化是针刺通过减少能量摄入,增加能量消耗达到减肥效应的形态学依据。
In present study, optic and electron microscopes were used to observe the fat tissue, small intestinal mucosa and liver tissue of obese rat. The results showed that as compared with normal rat there were many morphological changes in the obese rat. The brown fat cells were enlarged, full and fat drops enlarged too, the number of mitochondrion and blood capillary decreased in obese rat. After acupuncture treatment, above changes reversed markedly. This paper provided one of important morphological bases for acupuncture antiobesity which was achieved by enhancing energy consumption and reducing energy intake.

关键词(KeyWords): 针刺;单纯性肥胖症;线粒体;乳糜管

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基金项目(Foundation): 国家自然科学基金!(No.39270838)

作者(Author): 刘志诚,孙凤岷,王耿,魏群利,苏静,许建阳,项晓人
Liu Zhicheng, et al (Nanjing University of TCM, Nanjing, 210029 )

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