晏义平,孙凤艳
Yan Yiping (Department of Pharmacology, Medical College of Shantou University, Shantou, 515031) Sun Fengyan (State Key Laboratory of Medical Neurobiology, Shanghai Medical University, Shanghai, 200032)

• 1:广东省汕头大学医学院药理教研室!汕头515031
• 2:上海医科大学医学神经生物学国家重点实验室!上海200032

摘要(Abstract)：

本研究运用TUNEL染色法观察电针对大鼠脑缺血后脑内神经细胞凋亡的影响。结果显示：在假手术组和单纯电针组，大鼠脑内未见神经细胞凋亡，脑缺血后12小时，大脑皮层梗塞区内大量的神经细胞凋亡，在缺血十电针组，大脑皮层梗塞区内神经细胞凋亡数目显著减少。结果表明：电针抑制脑缺血后脑内神经细胞凋亡。
In this study, TUNEL staining was used to observe the effect of electro-acupuncture(EA) on apoptotic neuronal death induced by focal cerebral ischemia in rats. The results were as follows: In the sham-operated group and the EA treated group, TUNEL positive stained cell was not detected in the brain. In the ischemic group, a large number of apoptotic neuronal cells were detected in the infarcted area of cerebral cortex at 12h postischemia. In the ischemia + EA treated group, the number of apoptotic neuronal cells in the infarcted area reduced significantly. The results suggest that EA inhibits apoptotic neuronal death induced by focal cerebral ischemia.

关键词(KeyWords)： 脑缺血;凋亡;电针

Abstract:

Keywords:

基金项目(Foundation): 国家教委博士点基金

作者(Author): 晏义平,孙凤艳
Yan Yiping (Department of Pharmacology, Medical College of Shantou University, Shantou, 515031) Sun Fengyan (State Key Laboratory of Medical Neurobiology, Shanghai Medical University, Shanghai, 200032)

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参考文献(References)：

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